Annual Survey of Manufacturers ASM provides sample estimates of statistics for all manufacturing establishments with one or more paid employee.
County Business Patterns Some basic industry information on the county level is available here.
Economic Census The Economic Census is the U.S. Government's official five-year measure of American business and the economy.
PolicyMap Online GIS mapping tool that allows users to integrate over 15,000 data indicators from a variety of sources without having to download software. Covers economic and income information for national, state, and local areas.
Statistics of U.S. Businesses include number of firms, number of establishments, employment, and annual payroll for most U.S. business establishments. The data are tabulated by geographic area, industry, and enterprise employment size.